Inventory should help decisions, not hide them. A simple cleanup routine makes useful items easier to find during combat and exploration.
Keep consumables easy to find
Potions, scrolls and situational tools are more valuable when they are visible at the moment you need them.
Separate active gear from experiments
Move unused alternatives away from the main loadout until you are ready to compare them.
Remove obvious clutter regularly
Selling or moving low-value items keeps later decisions fast.
Distribute items by likely user
Put items on the characters most likely to use them so access is faster in combat.